Suppose a package has been running for quite a long time or has been mistakenly run and we would like to stop its execution.
To do so
Right Click on SSISDB Select All Execution Reports
Filter it to see all the Running packages

We can see our all the running packages there.

Now to stop any specific package, right click SSISDB and select Active Operations

From the Active Operation window, select the running job and click on Stop button to stop its execution.

Another option is to use the stored procedure à get the operation id of the running package and execute the stored procedure

Exec catalog.stop_operation @operation_id =199915

Hope it helps..