Recently while developing SSIS packages, the Visual Studio (SSDT) got crashed.
After restarting the Visual Studio and trying to execute the package we got the below error.
System.IO.IOException: The process cannot access the file ‘c:\folder\ssisproject.ispac’ because it is being used by another process.at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
at System.IO.File.Delete(String path)
at Microsoft.DataTransformationServices.Project.DataTransformationsProjectBuilder. IncrementalBuildThroughObj(IOutputWindow outputWindow)
at Microsoft.DataTransformationServices.Project.DataTransformationsProjectBuilder.
BuildIncremental(IOutputWindow outputWindow)
ISPAC file is the integration services project deployment file containing the packages and the parameters.
The fix is to open task manager and end the DtsDebugHost.exe task.

DtsDebugHost.exe is the SSIS Debug runtime process that executes the package.
Hope it helps..